Skip to main content
Natasha Lyonne
★ Acting

Natasha Lyonne

Born 1979 · New York City, New York, USA · Active 1944–2026

Born in 1979 in New York City, Natasha Lyonne is an actress known for her distinctive raspy voice and tough persona. She appears in Freeway II: Confessions of a Trickbaby (1999), where her character navigates a gritty underworld, and Madhouse (2004), which blends horror and dark comedy. Lyonne's career began as a child actress, but she found her niche in independent films and cult classics, solidifying her status in the realm of exploitation cinema. Her performances resonate with fans of the genre, making her a vital part of the SassyFlix catalog.

▶ Watch on SassyFlix 2 films available
Madhouse

Madhouse

2004 ★ 5.7
as Alice

A young psychiatric intern unearths secrets about the mental health facility in which he works. The film opens with a flashback depicting a young boy attempting to escape from Cunningham Hall Mental Facility before getting hit by a car and presumed dead. In the present day, psychiatric intern Clark Stevens (Joshua Leonard) come to Cunningham Hall to train before he can graduate to medical school. Inside, he meets some of the patients and is welcomed by Nurse Betty, who gives him keys to and a walkie-talkie before taking him to the director of the facility, Dr. Albert Franks (Lance Henriksen). On the way, however, they are interrupted by a patient named Carl, who claims that he "shouldn't be here," and patients aren't allowed to go home when they're mentally stable. Betty shrugs the accusations off and pushes Carl away. In Dr. Franks' empty office, Clark finds a book titled Psychology and the Paranormal, which implies connections between mental stability and the paranormal. Franks arrives and converses with Clark about the facility and its patients, with Clark suggesting some improvements for the building, but Franks replies sternly and bluntly before introducing him to Dr. Morton and Dr. Douglas. Clark now meets Nurse Sara (Jordan Ladd), who takes Clark on a tour around the facility. As they leave, mental patient Alice (Natasha Lyonne) sits watching a window, where she sees flashes of a demonic-looking boy. Sara talks privately with head nurse Annabelle Hendricks before finishing the tour with the basement cells, where the most dangerous patients are kept - a place nicknamed "Madhouse." One of the patients attacks Clark with a shard of glass but is beaten down by Drake, a gruff security guard. Later at night, Clark witnesses a young boy running around before going to help with a "situation in the rec room," where he watches Hendricks repeatedly shock Alice with a stun gun over medication until she is saved by Carl. Clark sees the boy again and pursues him to the Madhouse but only finds Dr. Morton, who recalls a patient from Cell #44, who escaped but apparently died; however, Morton believes him to still be alive and back in the facility. Before he can continue, Hendricks arrives and gives Clark the task of cleaning up a mess in the rec room. Sometime later, Clark retells the Cell #44 story to Franks, who curtly dismisses him. When Clark leaves the office, he overhears Franks arguing with Hendricks about how "she knows." Soon after, Sara is requested at the nurses' station for night duty. In the nurses' station, Sara and Hendricks hear a mysterious sound. Hendricks, equipped with her stun-gun, investigates the source and is attacked by a cloaked figure who electrocutes her to death with a defibrillator. The next day, Hendrick's body is taken away, and Franks assigns staff to interview patients about the murder, with Clark being assigned to the Madhouse. Clark goes to Cell #44, where the patient - who identifies himself as Ben London - tells Clark that if he's looking for the murderer, "the top of the food chain is a good place to start," which Clark infers to be Franks. Sometime later, Clark asks Grace (the nurse in charge of medicine) what Ben's prescription is and what it's for. Grace replies that everyone in the Madhouse are on the same drugs, and Clark takes a bottle for examination. Sometime later, Clark attempts to confront Sara with some questions about the facility but is unable due to a nurse discovering Carl has hung himself. In a meeting led by Clark and Sara, Alice talks about seeing the young boy, saying he makes sure that she "never forgets what madness feels like." Afterwards, Clark witnesses Drake having sex with a patient in an open room. Waking up the next morning, Clark gets a phone call from Sara that Drake is the murderer and has been arrested by the police. Later, Clark and Sara are trying to solve what is happening in the Madhouse but put the mystery on hold as they spend an intimate night with each other. Taking Ben's advice, Clark does some research on Franks and the medication. It is revealed that Franks has been using placebos on the patients and embezzling all the funding for himself. Meanwhile, the same apparition that killed Hendricks kills Dr. Morton with an axe. The next night, Clark confronts Ben again and is only told "The truth is right in front of you." Clark goes to Sara with what he knows, and she gives him some coffee filled with sleeping pills. While dreaming, Clark is haunted by Ben's voice of the cryptic inmate and visions of the little boy before realizing that Sara is the killer. Clark wakes up and fights the effects of the drugs long enough to get back to the Madhouse to talk to Ben, who reveals himself as the little boy, who quickly grows up into Clark. Apparently, Clark was Ben who ran away as a little boy and was presumed dead when Franks ran him over. The real Clark died, and Ben took his identity to get back into the Madhouse. Ben begins to remember killing Dr. Douglas and Nurse Polly. Ben confronts Franks in his office, attempting to flee and destroy all evidence of his embezzlement, and tells Franks who he really is right before killing him with the axe. Sara sees this and runs to the Madhouse. Ben tells her that he returned to the facility to make it better, and to get rid of everyone who didn't try to help him. Sara tries to convince Ben that he shouldn't kill her because he loves her, but he soon overpowers her before bringing the axe down on her, the screen going black before it makes contact. In the final scene, Ben is shown entering another mental health facility, dressed as "Clark" was in the beginning.

Watch Now
Career Highlights Top 6 by popularity · TMDB

Filmography

198 credits
2020s 29 credits
2026
Movie
2026
Roommates as Hannah
Movie ★ 6.6
2026
Movie
2025
Smurfs as Mama Poot (voice)
Movie ★ 5.8
2025
Movie ★ 7.0
2025
The Bad Guys 2 as Doom aka Susan (voice)
Movie ★ 7.7
2025
Movie ★ 6.5
2025
Everybody's Live with John Mulaney as Self - Director, Performer and Writer
TV ★ 5.0
2025
TV ★ 8.1
2024
Movie ★ 6.8
2024
Movie ★ 7.0
2024
Lightscape as Woman in Hotel
Movie
2024
TV ★ 6.8
2023
Poker Face as Charlie Cale
TV ★ 7.5
2022
Movie ★ 6.4
2022
Movie ★ 7.0
2022
DC League of Super-Pets as Merton (voice)
Movie ★ 7.2
2021
Movie ★ 6.5
2021
What If...? as Byrdie (voice)
TV ★ 8.1
2020
Movie ★ 6.9
2020
Movie ★ 6.0
2020
Lip Service as Risa The VO Agent
Movie
2020
Movie ★ 4.8
2020
Awkwafina Is Nora from Queens as Woman in Hair Salon
TV ★ 6.9
2020
Crossing Swords as Norah (voice)
TV ★ 6.0
2010s 69 credits
2019
Uncut Gems as Boston Player Personnel (voice)
Movie ★ 7.2
2019
Movie ★ 7.0
2019
Movie ★ 7.0
2019
Ad Astra as Tanya Pincus
Movie ★ 6.1
2019
Oh Jerome, No as Gretchen
TV ★ 6.2
2019
Russian Doll as Nadia Vulvokov
TV ★ 7.4
2019
Steven Universe Future as Smoky Quartz (voice)
TV ★ 8.2
2019
Euphoria as Hooker
TV ★ 8.3
2018
Movie ★ 6.5
2018
Show Dogs as Mattie
Movie ★ 6.0
2018
Doulo as Rena
Movie
2018
Family as Juggalette (uncredited)
Movie ★ 6.5
2018
Ballmastrz: 9009 as Gaz Digzy (voice)
TV ★ 6.6
2018
Explained as Narrator (voice)
TV ★ 7.5
2017
Handsome: A Netflix Mystery Movie as Detective Fleur Scozzari
Movie ★ 5.3
2017
Girlfriend's Day as Mrs. Taft
Movie ★ 5.0
2017
Movie ★ 4.3
2017
Big Mouth as Suzette (voice)
TV ★ 7.6
2017
Big Mouth as Ms. Dunn (voice)
TV ★ 7.6
2016
Yoga Hosers as Tabitha
Movie ★ 4.6
2016
Movie ★ 5.9
2016
Movie ★ 5.0
2016
Movie ★ 5.2
2016
Movie ★ 6.8
2016
Movie ★ 4.9
2016
TV ★ 7.5
2016
TV ★ 7.0
2016
Match Game as Self - Panelist
TV ★ 6.4
2015
Movie ★ 5.3
2015
Movie ★ 6.3
2015
#Horror as Emma
Movie ★ 3.5
2015
Movie ★ 6.4
2015
Movie ★ 3.9
2015
TV ★ 5.2
2015
Documentary Now! as Carla Meola
TV ★ 7.1
2015
TV ★ 6.1
2014
G.B.F. as Mrs. Hoegel
Movie ★ 6.0
2014
Movie ★ 4.2
2014
The Quitter as Gloria
Movie
2014
TV ★ 5.2
2014
TV ★ 5.8
2014
TV ★ 4.5
2014
TV ★ 5.2
2013
The Rambler as Cheryl
Movie ★ 4.8
2013
Movie ★ 4.2
2013
7E as Yael
Movie ★ 3.8
2013
Clutter as Lisa Bradford
Movie ★ 6.0
2013
Orange Is the New Black as Nicky Nichols
TV ★ 7.6
2013
Steven Universe as Smoky Quartz (voice)
TV ★ 8.4
2012
Movie ★ 6.3
2012
Movie ★ 5.6
2012
Movie ★ 4.8
2012
Girls as Rickey
TV ★ 6.4
2012
TV ★ 6.2
2012
TV ★ 7.9
2011
Night Club as Mrs. Keaton
Movie
2011
New Girl as Gretchen
TV ★ 7.4
2011
Portlandia as Madison
TV ★ 7.0
2011
Portlandia as Laura's Friend
TV ★ 7.0
2011
Portlandia as Danielle
TV ★ 7.0
2011
Portlandia as Carrie's Friend #2
TV ★ 7.0
2010
All About Evil as Deborah Tennis
Movie ★ 5.9
2010
Jelly as Mona Hammel
Movie ★ 7.0
2010
Movie ★ 10.0
2010
Gavin McInnes is a Fucking Asshole as Self (archive footage)
Movie
2010
Conan as Self
TV ★ 7.2
2000s 35 credits
2009
Movie ★ 3.5
2009
Movie
2009
Loving Leah as Esther
Movie ★ 6.9
2009
Goyband as Fani
Movie ★ 4.0
2009
TV ★ 5.0
2009
RuPaul's Drag Race as Self - Guest Judge
TV ★ 7.5
2008
Movie ★ 5.0
2008
Free Radio as Natasha Lyonne
TV
2006
Child Star Confidential as Self (archive footage)
TV
2005
Movie ★ 6.0
2005
Movie ★ 5.6
2005
Robots as Loretta Geargrinder (voice)
Movie ★ 6.5
2005
Weeds as Tiffany
TV ★ 7.5
2004
Blade: Trinity as Sommerfield
Movie ★ 5.9
2004
Madhouse as Alice
Movie ★ 5.7
2004
Movie ★ 6.0
2003
Party Monster as Brooke
Movie ★ 5.8
2003
Die, Mommie, Die! as Edith Sussman
Movie ★ 6.6
2003
Old School as Sara
Movie
2003
TV ★ 5.6
2002
Movie ★ 5.3
2002
Movie ★ 4.8
2002
Zig Zag as Jenna the Working Girl
Movie ★ 5.8
2002
Plan B as Kaye
Movie ★ 4.5
2001
American Pie 2 as Jessica
Movie ★ 6.3
2001
Movie ★ 6.3
2001
Movie ★ 6.6
2001
Fast Sofa as Tamara Jenson
Movie ★ 4.1
2001
Movie ★ 5.8
2001
Night Visions as Bethany Daniels (segment "If a Tree Falls...")
TV ★ 7.1
2001
TV ★ 6.8
2000
Movie ★ 7.1
2000
Movie ★ 6.5
2000
Movie ★ 5.6
1990s 13 credits
1999
American Pie as Jessica
Movie ★ 6.6
1999
Detroit Rock City as Christine
Movie ★ 6.8
1999
The Auteur Theory as Rosemary Olsen - Finalist
Movie ★ 4.6
1999
TV ★ 7.9
1999
TV ★ 9.1
1998
Movie ★ 4.9
1998
Movie ★ 4.6
1998
Slums of Beverly Hills as Vivian Abromowitz
Movie ★ 6.3
1998
Will & Grace as Gillian
TV ★ 6.9
1997
The View as Self
TV ★ 4.4
1996
Everyone Says I Love You as Djuna 'D.J.' Berlin
Movie ★ 6.5
1993
Movie ★ 5.9
1990
Movie ★ 3.0
1980s 4 credits
1989
Movie ★ 6.0
1989
The Simpsons as Sophie (voice)
TV ★ 8.0
1986
Heartburn as Rachel's Niece (uncredited)
Movie ★ 6.0
1986
TV ★ 7.1
1970s 2 credits
1975
Saturday Night Live as Self - Host
TV ★ 6.9
1975
Saturday Night Live as Self - Cameo (uncredited)
TV ★ 6.9
1940s 1 credit
1944
Golden Globe Awards as Self - Presenter
TV ★ 7.2
s 5 credits
Movie
Can We Talk? as Joan Rivers
Movie
Darlene as Annie
Movie
Crew Credits
2020s 18 credits
2025
Movie ★ 6.4
2025
All Heart Executive Producer
Movie ★ 3.0
2024
His Three Daughters Executive Producer
Movie ★ 6.8
2024
Movie ★ 6.0
2024
Movie ★ 6.0
2024
TV ★ 6.8
2023
Poker Face Executive Producer
TV ★ 7.5
2023
TV ★ 7.5
2023
Poker Face Director
TV ★ 7.5
2022
Crush Producer
Movie ★ 7.4
2022
Sirens Executive Producer
Movie ★ 5.4
2022
Loot Executive Producer
TV ★ 6.8
2021
Happily Thanks
Movie ★ 5.8
2020
Movie ★ 5.4
2020
Movie ★ 5.4
2020
Movie ★ 5.4
2020
TV ★ 7.6
2020
TV ★ 6.9
2010s 9 credits
2019
Russian Doll Executive Producer
TV ★ 7.4
2019
TV ★ 7.4
2019
TV ★ 7.4
2019
TV ★ 7.4
2019
TV ★ 7.4
2017
Movie ★ 4.3
2017
Movie ★ 4.3
2016
Antibirth Producer
Movie ★ 5.0
2013
TV ★ 7.6
2000s 3 credits
2004
Movie ★ 6.0
2003
Old School Producer
Movie
2000
Movie ★ 5.6
s 10 credits
2034 Story
Movie
Movie
Movie
Movie
Movie
Bambo Director
Movie
Bambo Writer
Movie
Bambo Producer
Movie
Darlene Producer
Movie
Red Sea Producer
Movie