CHATTERBOX!

Penelope, a young hairdresser, discovers her vagina can talk when it criticizes a lover's performance, who leaves in a huff. At the salon where she works, her talking vagina insults a lesbian client, who mistakes it for Penelope flirting with her, which leads to her being fired. Penelope goes to a psychiatrist, Dr. Pearl, where she reveals her "problem". In the psychiatrist's office, her vagina reveals a new talent, singing. It has a propensity for singing show tunes. Dr. Pearl reveals her secret to friends of his in show business. At a meeting of the American Medical Association, Penelope and her talking vagina, now called "Virginia", are revealed to the public for the first time. Virginia regales the assembled physician with show tunes. Dr. Pearl becomes her agent, and over Penelope's objections, launches Penelope and Virginia on an entertainment career. At a show hosted by Professor Irwin Corey, Virginia sings in public for the first time, becoming a star after crooning a disco tune. Virginia increasingly becomes the tail that wags the dog, with Penelope becoming increasingly unhappy as "they" become a successful act on a cross-country tour. Despite her new success, Penelope decides to kill herself until she sees the lover from the start of the movie and discovers that he has a talking penis.

Penelope becomes a star thanks to Virginia's singing but grows increasingly unhappy with her situation. Ultimately, she contemplates suicide, but changes her mind upon discovering her former lover has a talking penis.

The ending of Chatterbox! takes the film’s absurd premise to its logical, tongue-in-cheek conclusion: Penelope’s misery and sense of alienation are upended by the revelation that she’s not alone in her bizarre predicament. The discovery of another talking (and male) body part lampoons both sexual politics and the search for identity, offering a final wink to the audience about the universality—and comedy—of human quirks.