Allison from Ohio comes to New York City to escape an abusive husband and ends up entangled with murderous female vigilantes who routinely castrate suspected rapists and batterers. Allison's dilemma begins when she is attacked on a city bus. Before she is harmed, five masked women pounce upon the attacker, deftly emasculate him and then kill him.
Allison tries to flee, but the women surround her and demand that she join them to prevent her from going to the police. They ask her name; thinking quickly, she takes the name "Jennifer" from a nearby storefront.
Jesse is the psychotic leader of the group and takes them on an increasingly crazed city-wide spree that results in the deaths of numerous well-to-do misogynists. As they slash their way across the city, the vengeful femmes are pursued by Billie Perez, a female cop determined to stop them.
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